Předmět Biologie I - přednáška (aVLBI0121p)

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Materiál	Typ	Datum	Počet stažení

Cíl

After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.

Osnova

Week 1: 21. – 25.9. 2015Introduction to medical biology - from understanding of cellular principle to modern biomedicine (prof. Ing. Petr Dvořák, CSc.)Week 2: 28.9. – 2.10.Basic architecture and function of eukaryotic cells (prof. MUDr. Augustin Svoboda, CSc.)Week 3: 5.10. – 9.10.Plasma membrane structure and function (prof. MUDr. Augustin Svoboda, CSc.)Week 4: 12.10. – 16.10.Molecular mechanisms of cell adhesions and intercellular communications (Mgr. Kateřina Cetkovská)Week 5: 19.10. – 23.10.Cytoskeleton and cell migration in health and disease (prof. MUDr. Marie Kopecká, CSc.)Week 6: 26.10. – 30.10.Mitosis and cytokinesis in normal and cancer cells (prof. MUDr. Marie Kopecká, CSc.)Week 7: 2.11. – 6.11.Molecular mechanisms regulating cell cycle and cell proliferation (Mgr. Stjepan Uldrijan, CSc.)Week 8: 9.11. – 13.11.Architecture, molecular biology and pathology of eukaryotic cell nucleus (doc. MUDr. Iva Slaninová, Ph.D.)Week 9: 16.11. – 20.11.Biosynthesis of proteins in eukaryotic cells (RNDr. Mário Špírek, Ph.D.)Week 10: 23.11. – 27.11.Regulation of gene expression - principles and examples (prof. MUDr. David Šmajs, Ph.D.)Week 11: 30.11. – 4.12.Cell death - mechanisms, implication for medical research (doc. MUDr. Iva Slaninová, Ph.D.)Week 12: 7.12. – 11.12.Introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)Week 13: 14.12. – 18.12.no lecture - dissection weekWeek 14: 21.12.-23.12.Substitution lectureWeek 15: 4.1. – 8.1. 2016Basic principles and molecular mechanisms regulating early development of mammals - physiology and pathology (Yuh-Man Wadeley, M.Sc., Ph.D.)

Literatura

povinná literaturaEssential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009. 1 v. (vari. ISBN 978-0-8153-4130-7. infoMedical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013. 1 online r. ISBN 9781118689028. infodoporučená literaturaHARDIN, Jeff, Gregory BERTONI a Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012. xxviii, 79. ISBN 0321689631. infoLODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008. xxxvii, 11. ISBN 978-0-7167-7601-7. infoPrinciples of genetics. Edited by D. Peter Snustad - Michael J. Simmons. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009. xix, 823 s. ISBN 9780470388259. infoThe biology of cancer. Edited by Robert A. Weinberg. 2nd ed. ISBN 9780815342205. infoPrinciples of development. Edited by Lewis Wolpert. 2nd ed. Oxford: Oxford University Press, 2002. xxv, 542 s. ISBN 0-19-879291-3. infoneurčenoCAMPBELL, Neil A. a Jane B. REECE. Biology. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005. xl, 1231 s. ISBN 0-8053-7146-X. info

Požadavky

Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture are specified in the course syllabus. Corresponding study literature is detailed in the interactive syllabus of the course.

Garant

prof. Ing. Petr Dvořák, CSc.

Vyučující

Mgr. Kateřina Cetkovskáprof. Ing. Petr Dvořák, CSc.prof. MUDr. Marie Kopecká, CSc.doc. Mgr. Lumír Krejčí, Ph.D.Mgr. Pavel Krejčí, Ph.D.Mgr. Vladimír Rotrekl, Ph.D.doc. MUDr. Iva Slaninová, Ph.D.prof. MUDr. Augustin Svoboda, CSc., dr. h.c.prof. MUDr. David Šmajs, Ph.D.RNDr. Mário Špírek, PhD.Mgr. Stjepan Uldrijan, CSc.doc. Yuh-Man WadeleyMgr. Hana HříbkováMgr. Kateřina Vopěnková, Ph.D.Mgr. Martina Vráblíková