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Předmět Farmakologie (DA0107362)

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Další informace

Sylabus

The syllabus Pharmacology 2nd Medical FacultyLectures and SeminarsIntroduction to PharmacologyBasic terminology, types of treatment, development of new drugs, medicines actGeneral pharmacologyPharmacokineticsAbsorption, distribution, elimination and biotransformation of drugsReceptor theory, mechanism of drug actionsMechanism of regulation, receptors, mediatros, agonists, antagonistsInteractions of drugsMutual effects of drugs, toxicityDevelopment of new drugsDevelopment of new drug, preclinical and clinical assessment, registrationSpecial pharmacologyPharmacology of the autonomic nervous systemPhysiology, receptors, mediators, agonists, antagonists, mechanism of actionParasympathetic nervous system - parasympathomimetics, parasympatolyticsSympathetic nervous system - agonists, antagonists, sympathomimetics, sympatholyticsCardiovascular systemAntiarhytmic drugsCardiac Arrhytmias, drugs affecting heart output, heartrate, classificationTherapy of heart failureHeart failure, digitalis, positive inotropic effect, cardiac hypertrophyBeta blockersBeta receptors, classification, Clinic use and strategiesDrugs used in blood coagulation disorders DiureticsMechanism of action, classificationRespiratory systemDrugs for Asthma treatment, mucolytics, cough preparationsAntihistminesHistamin, pathofysiology, effects, H1 and H2 agonists, clinical use 1st and 2nd generationDrugs used in GITDrugs and the liver, therapy of peptic ulcers, spasmolytic agents, motility stimulating agents, laxatives, therapy of diarhoeHypolipidemic drugsTypes of pareticles, types of disorders, statins, fibrates, nicotin acidDrugs used in rheumatic disease and OANSAIDs, SYSADOA, DMOAAnalgetics - antipyreticsEffects, mechanism of action, dosage, main groupsAnalgetics - opioidsMorfin and its derivates, analgetic receptors, mechanism of action, clinical use, combinations of analgeticsGeneral anaestheticsNeuromuscular blocking agents, classification, mode of actionAntibioticsClassification and indications, mechanism of actionPenicillins, Cephalosporins, Macrolides, Tetracyclins, Aminoglycosides, Quinolones, CombinationAntiviral DrugsClassificaton, specific use, AIDS, toxicityAntidiabetic drugsClassification, mechanism of action, oral antidiabetic drugs, insulinsCentral nervous system PharmacologyMediators of CNS, classification, hypnotics and anxiolytics, drugs used in psychoses, antidepressant drugs, neuroprotective drugsKorikosteroidsPathophysiology, effects, indications, risksDrug policyRationa, pharmacotherapy, drug reimbursement, drug utilizationSeminarsGeneral pharmacologyPrescrtiption of DrugsIntroduction to rational drug prescribingPatient-drug concept

Literatura

Rang, H. P.: Pharmacology : Churchill Livingstone, 2012 (B), (available as ebook)+Neal, M. J.: Medical pharmacology at a glance : Blackwell Science, 2012 (B)+Katzung, B. G.: Basic & clinical pharmacology : Lange, 2012 (B)+Howland, R.D.: Pharmacology : Lippincott‘s Illustrated Reviews 2008+ Dale, N.N.: Pharmacology condensed : Churchill Livingstone, 2009 (B)+British National Formulary No. 62 (or higher) - BMJ Books

Garant

doc. MUDr. Zoltán Paluch, Ph.D., MBA