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Předmět Interna I (DA0108369)

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Sylabus

Syllabus of lectures of Internal Medicine IPulmonology: Emergency situation in pulmonology The presentation gives an overview of emergency situations in pneumology, their etiology, pathogenesis, clinical features, diagnosis and treatment. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Bronchoscopy Overwiev of indications, types, complications and benefits of this important examination. Recquired knowledge: anatomy, physiology of lungs and ventilation Acute and chronic respiratory insuficiency The lecture deals with the definition, pathophysiology, clinical presentation, diagnostic approaches and therapeutic measures in conditions associated with respiratory insufficiency. Recquired knowledge: anatomy, physiology of lungs and ventilation COPD Etiology, pathophysiology, risk factors. Clinical presentation, physical examination, functional testing, imaging methods. Therapy and importace of non-smoking. Recquired knowledge: anatomy, physiology of lungs and ventilation Dyspnoe The presentation gives an overview of the etiology, pathogenesis, clinical features, diferential diagnosis and treatment of dyspnoea. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Ashtma bronchiale The presentation gives an overview of the definition, etiology, pathogenesis, clinical features, diagnosis, classification and treatment of bronchial asthma. The latest international guidelines are considered (GINA). Recquired knowledge: anatomy, physiology of lungs and ventilation Intersticial lung diseases The lecture deals with the definition, pathophysiology, clinical presentation, diagnostic approaches and therapeutic measures in interstitial pulmonary processes, as disease model is discussed sarcoidosis in detail. Idiopathic pulmonary fibrosis - the presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of idiopathic pulmonary fibrosis. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Haemopthysis (as. Trefný) The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diferential diagnosis and treatment of haemoptysis. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Pneumonias (prim. Petřík) The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of community acquired and hospital acquired pneumonia and pneumonia in immunocompromised host. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Pleural effusion (prof. Marel) The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of pleural effusion. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of lungs and ventilation Tuberculosis (prim. Petřík) The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of tuberculosis. Particular attention is paid to new methods of diagnosis of latent tuberculosis, vaccination and other measures of control of tuberculosis. Recquired knowledge: anatomy, physiology of lungs and ventilation, microbiology of tbc Lung cancer (prof. Marel) The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of lung cancer. Particular attention is paid to imaging methods and prevention of this disease. Recquired knowledge: anatomy, physiology of lungs and ventilationGatroenterology: Examination methods in gastroenterology and hematology History, common complaints. Physical examination. Ultrasound, X-ray, CT and MR imaging. Endoscopic and biochemical methods. Recquired knowledge: anatomy, physiology of gastrointestinal tract Gastroesophageal reflux disease. Peptic ulcer of stomach and duodenum The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of gastroaesophageal reflux disease and peptic ulcers. Particular attention is paid to imaging methods and prevention of this disease. Recquired knowledge: anatomy, physiology of gastrointestinal tract Tumours of stomach, nonspecific inflammatory bowel disease The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of stomach tumours and nonspecific inflammatory bowel disease. Particular attention is paid to imaging methods. Recquired knowledge: anatomy, physiology of gastrointestinal tract Intestinal polyps, cancer of large intestine and rectum The presentation gives an overview of the epidemiology, etiology, pathogenesis, clinical features, diagnosis and treatment of intestinal polyps and cancer. Particular attention is paid to imaging methods, screening and prevention of this disease. Recquired knowledge: anatomy, physiology of gastrointestinal tract Gastrointestinal bleeding, chronic pancreatitis Acute bleeding to the gastrointestinal tract, main clinical symptoms, differences in clinical symptomatology dependend on etiology of the bleeding. Importance of circulation stabilization, endoscopy methods for examination and treatment. Chronic pancreatitis - definition, pathogenesis, etiology. Risk factors, clinical presentation, physical examination, lab results and imaging methods. Treatment. Recquired knowledge: anatomy, physiology of gastrointestinal tract Cholelithiasis and its complications Definition: Cholecystolithiasis - biliary stones in the gallbladder, choledocholithiasis - biliary stones in the common bile duct and hepatic duct. Incidence, etiology, clinical presentation, laboratory results, imaging methods, therapy. Recquired knowledge: anatomy, physiology of hepatobiliary area Chronic hepatitis, cirhosis of the liver Definition, ethiology and pathophysiology. Viral, autoimmune and other chronic hepatitis. Diagnosis, imaging methods, treatment and complications of this disease. Liver cirhosis - etiology, pathophysilogy, clinical presentation, lab and imaging methods. Treatment and complications. Recquired knowledge: anatomy, physiology of liver Portal hypertension, hepatic failure Definition, anatomy and pathophysiology of portal hypertension. Ethiology, diagnostis, clinical presentation, complications and therapy. Definition and incidence of liver failure, ethiology and pathophysiology, complications, diagnosis and treatment. Recquired knowledge: anatomy, physiology of liver Differential diagnosis of jaundice (as. Lochmannová) Review of basic types of icterus, (prehepatal, hepatal, posthepata), clinical presentation, lab results, imaging methods. Case reports. Recquired knowledge: anatomy, physiology of liver Differential diagnosis of fever states (as. Holá) Pathophysiological of temperature, types of temperature, diagnostic methods. Febrile states by etiology: infectional, tumors, systematic disease. Subfebrile states, invasive methods as febrile source. Recquired knowledge: physiological and pathophysiological knowledge of thermoregulationDiabetology a metabolism: Diabetes mellitus part I Ethiology, pathogenesis, clinical presentation, diagnostic. Classification and diferential diagnostics of diabetes. Recquiered knowledge: physiology and pathophysiology of metabolism Diabetes mellitus part II Acute and chronic diabetes complication. Clinical presentation, diagnostics and treatment. Recquiered knowledge: physiology and pathophysiology of metabolism Treatment of diabetes mellitus Treatment with oral antidiabetic agents and insulin treatment. Differeces in treatment of type 1 and 2 diabetes. Diet and physical exercise. Recquiered knowledge: physiology and pathophysiology of metabolism Nutritional disorders (obesity, kachexia), hyperuricaemia, porphyria Definition, measurement, clasification of obesity. Examination of an obese patient (history, specifics in obesity), function and distribution of adipose tissue, complication of obesity. Therapy (behavior modification, diet, exercise, psychotherapy, drugs, surgery). Definition, etiology of malnutrition, diagnostic and types, laboratory parametres, complications. Definition, patogenesis, clinical features of hyperuricaemia, artritis uratica, chronic gout, therapy. Definition, classification, clinical features of porfyria. Recquiered knowledge: physiology and pathophysiology of metabolism Disorders of lipid metabolism, atherosclerosis and endothelial dysfunction (as. Piťha) Dyslipidemia - risks and classification. Goals for treatment, recommended targets for dyslipidemia treatment. Lab results. Atherosclerosis, endothelial dysfunction. Recquiered knowledge: physiology and pathophysiology of metabolismCardiology: Acute coronary syndromes Ethiology, pathophysiology, risk factors. Clinical presentation, examination, diagnostics, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Atherosclerosis and chronic coronary heart disease Introductory lecture to clinical aspects of coronary heart disease (CHD) defining clinical forms of CHD. It defines principles of coronary circulation in a heathy individual, as well as normal functios of endothelium. Endothelial dysfunction is presented in relation to atherogenesis together with main risk factors of CHD. Of clinical forms of CHD, effort angina pectoris and silent ischemia are presented (clinical symptomatology, examinations, noninvasive and invasive treatment). Recquired knowledge: fysiology and pathophysiology of circulation Valvular heart disease Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Arrhythmias Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Congestive heart failure Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Cor pulmonale, pulmonary embolism Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Hypertension Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Shock Presentation composed of two parts. The general one defines symptoms and signs of shock, diagnostic principles, as well as general therapeutic possibilities. The second part presents cardiogenic shock in myocardial infarction, in pulmonary embolism and in cardiac tamponade. Oligemic shock is presented mainly in connections important for internal medicine. Distributory shock, septic and anaphylactic shock are presented. Recquired knowledge: fysiology and pathophysiology of circulation Cardiomyopathies Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Myocarditis, pericarditis, endokarditis Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Differential diagnosis of chest pains Ethiology, pathophysiology, risk factors. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation Basic ECG records Clinical presentation, basic ecg records of most important dysrrhytmias. Recquired knowledge: fysiology and pathophysiology of circulation Disorders of limb arteries and veins Ethiology, pathophysiology, risk factors of arterial and velus disease of peripheral vessels. Clinical presentation, imaging methods, treatment. Recquired knowledge: fysiology and pathophysiology of circulation

Literatura

Kasper, D. L.: Harrison ́s principles of internal medicine : Mc Graw-Hill, 2005 (B)Andreoli, T. E.: Cecil essentials of medicine : W. B. Saunders company, 2007 (B)Klener, P.: Vnitřní lékařství 1-4. vol. : Karolinum,2003 (B)Klener, P.: Vnitřní lékařství : Galén, 1999 (B)Klener, P.: Vnitřní lékařství : Galén, 2003 (B)

Garant

Prof. MUDr. Milan Kvapil, CSc., MBA