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Předmět Mikrobiologie II (FG10024)

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Další informace

Sylabus

LecturersAssoc. Prof. Vladimir Buchta, M.Sc., Ph.D.Zuzana Cermakova, D.V.M., Ph.D.Josef Scharfen, M.D., Ph.D.Vlasta Stepanova, M.D., Ph.D.LecturesIntroduction to General Bacteriology. Morphology, physiology and genetics of bacteria. Taxonomy. Pathogenicity, virulence factors.Virology. Taxonomy and morphology of viruses, pathogenesis of viral infections. Human viral infections, prevention, treatment.Foodborne infections.Vacctination-preventable infections. Tuberculosis. Mycobacteriosis. Nocardiosis.Sexually transmitted diseases. HIV, viral hepatitis.Respiratory infections. The flu.Parasitology, protozoa, helminth.Anthropozoonoses. Travel Infections. Tropical infections.Antibiotic resistance. General principles of antibiotic therapy, basic division of anti-infectives, medical significance of individual groups of ATB, resistance mechanisms.Hospital infections. Causative agents, symptomatology, diagnosis and treatment of nosocomial infectins, and blodstream infectionsPractical courses & seminarsLecturersAssoc. Prof. Vladimir Buchta, M.Sc., Ph.D.Zuzana Cermakova, D.V.M., Ph.D.Vlasta Stepanova, M.D., Ph.D.Sarka Lukesova, M.D., Ph.D.Josef Scharfen, M.D., Ph.D.Lenka Ryskova, M.D.Practical coursesThe Staphylococci.Diagnostics of staphylococci based on their biochemical properties. Staphylococcal toxins.  Overview to the clinical forms of the disease. The basics of therapy, the incidence of resistance to antibiotics, epidemiological context.The Streptococci.The most significant species - morphology, identification, virulence factors and pathogenicity, laboratory diagnosis, culture - conditions, growth characteristics, identification - bacitracin, optochin, deoxycholate, hemolysis.The Enterobacteria.Diagnostics, cultivation, identification (biochemical tests, agglutination), clinical significance.Bordetella sp., Hemofilus sp. Corynebacterium sp.The most important members of the genera. Cultivation, conditions, growth properties, virulence factors, identification and serotypization of the bacterial strains.Mycobacterium sp., Nocardia sp. Corynebacterium.Diagnosis of pathogenic and non-pathogenic species, staining methods, culture media, test of toxigenity of strainsPseudomonas sp. and other nonfermenting.Diagnosis of clinically significant non-fermenting rods. Meaning for opportunistic / hospital infections. Cystic fibrosis.Laboratory diagnosis of infections of the skin and soft tissues ;Presentation and Diagnosis of the most important causative agents (S. pyogenes, S. aureus, anaerobic bacteria)Laboratory diagnosis of respiratory tract infections.Presentation of diagnostics and therapy of the most common infections of the respiratory tract.Laboratory diagnosis of GIT infections.Presentation of diagnosis and treatment of the most common foodborne illness.Laboratory diagnosis of urinary tract onfections and sexually transmitted infection. Presentation diagnostics and therapy of the most common urogenital infections.Laboratory disngosis of bloodstream infections. Presentation diagnostics and therapy of the most common nosocomial infections, and bloodstream infectionsLaboratory diagnosis of CNS infections. Bacterial, viral infection. Direct detection, ELISA, PCR.Infection in immunosuppressed patients. Overview of the most common opportunistic agents (bacterial, viral, fungal and parasitic) infections in different groups of immunosuppressed patients, specificity of diagnosis Notes:Detailed information about microbiology lectures and practical classes you can find on the board on the first floor of the department of microbiology in the Faculty Hospital.

Literatura

Compulsory literatureW. Levinson, E. Jawetz. Medical Microbiology and Immunology. (4th ed.), Appleton and Lange, Stamford, 1996. ISBN 0-8385-6225-6 (and newer editions)Recommend literatureC. A. Mims et.al. Medical Microbiology. Mosby, 1993. ISBN 0-397-44631-4 (and newer editions)P. H. Gilligan et al. Cases in Medical Microbiology and Infectious Diseases (third edition). ASM Press, 2003. ISBN 1-55581-207-4Recommended study literature in electronic form:Entry: Medical library, Databases, Sample of Databases, Databases of e-books: 1. Ebrary Academic CompleteMedical Microbiology (7th Edition) Contributors: Murray, Patrick R. Rosenthal, Ken S. Pfaller, Michael A.September 2012  2.   Elselvier Key word: Microbiology C.A.Mims et. Al. Medical Microbiology. Mosby,1993 - 5th edition 2013  Notes:  Student must have a valid password of his university account 

Požadavky

Medical  Microbiology  -  General  Medicine Criteria for a credit - the academic year 2015/2016Credit: Participation in practical exercises - one absence is tolerated. For more absences (due to illness), a student must, in agreement with the teacher, develop seminar work.Protocols of exercises (all) with the appropriate formal processingIn the week from 04.01.2016 to 08.01.2016, students will write the credit test in the computer lab of Educational Center (20 questions, must get 70% points)  Groups:  Wednesday - Doc. BuchtaThursday -  Dr.Čermáková  Friday - Dr. Štěpánová   Final exam  2015/2016 exams will be listed in the electronic system SIS approximately as follows the number of students and the start time of the examination will be given in the SIS Forms laboratory protocols, lectures, addresses, contacts and other informationhttp://www.lfhk.cuni.cz/klinmikrob Notice: The principles of safety at work with infectious agents and stay in the space of the school (lab for training) are mandatory for all students. It is forbidden to move outside the school rooms.  

Garant

doc. MUDr. Helena Žemličková, Ph.D.