Předmět Patologická fyziologie I (FG10027)

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Materiál	Typ	Datum	Počet stažení

Sylabus

LecturersProf. Miroslav Kuba, M.D., Ph.D.Prof. Zuzana Kubova, M.D., Ph.D.Organism and Environment, Adaptation. Health Versus Disease, Clinical and Biological /Somatic/Death.  Etiology and Pathogenesis. (Kuba 3)Alterations in Fluid Volume. Disorders of Osmolarity, Etiology and Pathogenesis of Edema. Hyponatremia, Hypernatremia. (Kubova 3)Pathologic Changes in Immunoreactions. Inflammation. SIRS, Sepsis. (Kuba 3)Disorders of Calcium and Phosphorus Metabolism, Magnesium Imbalances. Osteoporosis, Osteomalacia, Renal Osteodystrophy. Tetany, Pathophysiology of Cramps/spasms, convulsions. (Kuba 3)Disorders of Peripheral Circulation. Circulatory Collapse, Syncope. Shock - Definition, Etiology, Pathogenesis.  Thrombogenesis. (Kubova 3)Leukemias - etiology and pathogenesis. Polycythaemia. Bone Marrow Depression. (Kuba 3)Blood Transfusion, Complications, Erythroblastosis Fetalis. Abnormalities of Haemostasis and Coagulation. (Kuba 3)Dyslipoproteinemia. Arteriosclerosis. Endotelial Dysfunction. Effects of Nitric oxide. (Kubova 3)Arterial Hypertension - Etiology and Pathogenesis. Arterial Hypotension. (Kuba 3)Pulmonary Circulation, Ventilation/Perfusion Ratio, Effect of Hypoxia. Ventilatory and Diffusion Lung Dysfunction. Obstructive Respiratory Diseases. Restrictive Pulmonary Diseases. (Kubova 3)Pulmonary Hypertension, Pulmonary Edema. ARDS. Respiratory Failure. Hypoxia. Hyperoxia, Hyperbaria, Decompression. (Kubova 3)Control of Cardiac Function, Disorders of rhythm and conduction. Ischemic Heart Disease. Myocardial Infarction and its Complications. Valvular Heart Disease. Congenital Heart Defects. (Kuba 3)Heart Failure - Etiology and Pathogenesis. Cardiac Compensatory Mechanisms - Myocardial Hypertrophy, Dilated Heart.Peripheral Compensatory Mechanisms in Heart Failure. (Kuba 3) Practical courses & seminarsLecturersProf. Miroslav Kuba, M.D., Ph.D.Prof. Zuzana Kubova, M.D., Ph.D.Assoc. Prof. Ing. Jan Kremlacek, Ph.D.Jana Langrova, M.D., Ph.D.Jana Szanyi, M.D., Ph.D.Seminars1. Introduction to practical classes.  Neoplasia,Neoplasm-Host Interaction (Effects).2. Disorders of acid-base balance. Hypokalemia, Hyperkalemia.3. Stress, General Adaptation Syndrome, Psychosomatic Diseases.TEST - homeostasis disorders9. Pathophysiology of Pain. TEST - haemostasis disorders10. Thermoregulation. Etiopathogenesis of fever. Practical courses4. ECG I - description5. ECG II - description. TEST - disorders of calcium metabolism6. ECG III - practice7. ECG IV - practice, self-ECG recordings8. ECG V - TEST11./12. Bicycle ergometry - adaptation of the cardio-vascular system to a physical load. 1/2 group12./11. Computer Spirometry - recordings and evaluation. 1/2 group13. Anemias - Etiology and Pathogenesis, Functional consequences, Compensation; Microscopic findings in peripheral blood.

Literatura

Compulsory literatureM. Kuba, Z. Kubova Pathophysiology- Basic overview for medical students. 1st. ed., The Karolinum Press, 2006. ISBN 80-246-1190-2S. A. Price, L. M. Wilson Pathophysiology-Clinical Concepts of Disease Processes. 5th ed., Mosby - Year Book Inc., 1997. ISBN 0-8151-6621-4. (4th edition from 1992 is also acceptable)Recommend literatureC. M. Porth Pathophysiology-Concepts of Altered Health States. 5th ed., J.B. Lippincott Comp. Philadelphia, 1998. ISBN 0-397-55413-3 S. J. McPhee et al. Pathophysiology of Disease (An Introduction to Clinical Medicine). 3rd ed., Lange Medical Book, 1997. ISBN 0-8385-8160-9 L. S. Lilly Pathophysiology of Heart Disease: a collaborative project of medical students and faculty. 2nd ed., Williams and Wilkins Baltimore, 1998. ISBN 0-683-30220-5 J. Ali, W. R. Summer, M. G. Levitzky Pulmonary Pathophysiology. 1st ed., McGraw-Hill New York 1999. ISBN 0-07-062170-5 L. Borska et al. EKG Desatero. 1st ed., MSD Brno -COPY 2006. ISBN 80-86633-52-7 

Požadavky

Credit: For credit, maximum one absence, passing of all written tests or oral examinations in seminars and practical classes and presentation of papers to given topics is required.Examination: Final exam is oral and includes one question in general pathophysiology and two questions in systemic pathophysiology. Obtaining of both credits (winter and summer term) is obligatory for the final exam.

Garant

prof. MUDr. Miroslav Kuba, CSc.