Předmět Základy odběru a konzervace tkání pro transplantace (FG50003)

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Materiál	Typ	Datum	Počet stažení

Sylabus

LecturesHistory of tissue banks, tissue donation - ethical and legal issues (EU Directives and national legislation of the Czech Republic), tissue harvests in living and cadaveric donors, cell and tissue graft processing, procurement establishment, tissue establishment (Mericka 2)Principles of preservation methods, hypothermic preservation, deep freezing, cryopreservation, theory of cryoprotection, vitrification and its application in cell and tissue banking, freeze-drying, methods of organ preservation, organ bank. (Mericka 2)Safety and quality assurance in practice of tissue establishments. Contraindications of tissue harvests, laboratory testing of donors and processed tissue grafts, importance of using clean room technology for safety of tissue transplantations,quality and safety assurnace systems, Quality and safety in the practice of the organ bank. (Mericka 2)Practical courses & seminarsLecturersPavel Mericka, M.D., Ph.D.Dr. Hana StrakovaMgr. Barbora HonegrovaSeminarsApplication of tissue grafts and advanced medicinal products in different medical disciplines - surgical disciplines, hematology and oncology. Advanced medicinal products for cell therapy. Methods of risk assesment and risk management in cell and tissue transplantation.Practical coursesOrganisation of tissue harvests in living and cadaveric donors,donor suitability - practical examples, demonstration of preservation methods and tissue grafts, documentation on tissue harvest and application. Use of clean room technology in processing of cell and tissue grafts, organ bankCryopreservation of cells and tissues, use of cell culture in clinical situations, advanced medicinal products, human milk bank, application of the system of Hazard Analysis and Critical Control Points in practice of tissue and milk banks

Literatura

Compulsory literatureWarwick,R.M. et al. Tissue and Cell Donation. An essential guide. Willey-Blackwell,Oxford 2009 -selected chaptersRecommend literatureBopp.,K.F. Guide to safety and quality assurance for organs,tissues and cells Council of Europe Publishing,Strasbourg 2002Collins,G.M.,Dubernard,J.M.,Persijn,G.G.,eds. Procurement,Preservation and Allocation of Vascularized Organs,Kluwer Academic Publ.,Dordrecht, Boston, London, 1997-selected chaptersSmit Sibinga,C.Th.,Das,P.C. Meryman,H.T., eds. Cryopreservation and Low Temperature Biology in Blood Transfusion,Kluwer Academic Publ. Dordrecht,Boston,London,1990-selected chapters

Požadavky

CreditAttendance in lectures, practical lessons and seminar.Preparation of seminar thesis.

Garant

MUDr. Pavel Měřička, Ph.D.