Předmět Infekce (EA0110025)

Na serveru studentino.cz naleznete nejrůznější studijní materiály: zápisky z přednášek nebo cvičení, vzorové testy, seminární práce, domácí úkoly a další z předmětu EA0110025 - Infekce, Lékařská fakulta Plzeň, Univerzita Karlova v Praze (UK).

Materiál	Typ	Datum	Počet stažení

Sylabus

 Lesson I  Gastrointestinal  diseases of infectious origin Pathophysiology of gastrointestinal diseases (osmotic, inflammatory, secretory mechanisms of diarrhoea)Incidence and epidemiology of infectious gastroenteritesInfectious gastroenteritis of viral and bacterial origin and foodborne toxigenic diarrhoea (clinical course, diagnosis, therapy, prophylaxis)Differential diagnosis of infectious and non- infectious diarrhoeaComplications of infectious diarrheal diseasesClinical picture, epidemiology, pathophysiology, complications, therapy, prophylaxis of Salmonellosis, Salmonella typhi and paratyphi, Cholera, E.coli gastroenteritis, Campylobacteriosis, Yersinia enterocolitica, Shigellosis, pseudomembranous enterocolitis, Rotavirus, Adenovirus, Norwalk virus gastroenterites and other viral gastroenterites, foodborne toxigenic diarrheaHemolytic-uremic syndromeAspects of prophylaxis of infectious diarrhea (vaccination) Lesson IIInfectious inflammatory diseases of the liver  Pathophysiology of viral hepatitesIncidence and epidemiology of viral hepatitesAcute viral hepatitis A - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers), therapy, prophylaxis specific and non-specificAcute viral hepatitis B - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers), therapy, prophylaxis specific and non-specificAcute viral hepatitis C - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers) therapy, possibility of prophylaxisViral hepatitis D - pathophysiology, epidemiology, clinical course, diagnosis (laboratory and                      serologic markers), therapy, possibility of prophylaxisAcute viral hepatitis E- pathophysiology, epidemiology, clinical course, diagnosis (laboratory and serologic markers) , therapy, prophylaxis         Viral hepatites G, F, TTV - new causes of viral hepatites?Complications and sequelae of acute viral hepatitesDifferential diagnosis of acute hepatites (infectious and non-infectious origin)Chronic hepatitites B and C - incidence, clinical picture, laboratory and serologic markers,                  possibility of therapy and prophylaxis nowadaysReye´s syndrome  Lesson III Exanthematic diseases Types of exanthems commonly, pathogenesisExanthematic diseases of bacterial and viral originScarlet fever - epidemiology, pathogenesis, clinical course, diagnosis, therapy, and differential diagnosisToxic shock syndrome - history, epidemiology, pathogenesis, clinical course, diagnosis, therapyKawasaki syndrome - history, epidemiology, pathogenesis, clinical course, diagnosis, therapyRubella - epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, complications, rubella in pregnancy, prophylaxisMeasles - epidemiology, pathogenesis, clinical course, diagnosis, complications, differential diagnosis, measles and immunity of organism, prophylaxisVaricella (Chickenpox) - epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, therapy, complications, varicella in pregnancy, varicella and immunodeficiency, prophylaxisHerpes zoster - epidemiology, pathogenesis, clinical course, diagnosis, therapyMegalerythema infectiosum - epidemiology, pathogenesis, clinical course, diagnosis, differential diagnosis, therapy, complications, megalerythema infectiosum in pregnancyExanthema subitum (Roseola infantum)- epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications  Lesson IV Lymphadenopathy Occurrence of lymphadenopathy commonly, quick diagnosis is necessaryViral causes of lymphadenopathy:Adenovirus - epidemiology, clinical course, diagnosis, therapyInfectious mononucleosis /virus Epstein-Barr, cytomegalovirus/ - epidemiology, pathogenesis, clinical course, diagnosis, therapy, complicationsParotitis epidemica (Mumps) - epidemiology, pathogenesis, clinical course, therapy, complications, therapy if complications, prophylaxisRubella, measles - clinical course exanthematic diseasesGingivostomatitis herpetica (Aphthous stomatitis) - epidemiology, pathogenesis, clinical course, therapy, differential diagnosis Bacterial cases of lymphadenopathy:Infections of streptococci - angina, lymphadenopathy - epidemiology, pathogenesis, clinical course, diagnosis, therapy, complicationsInfections of staphylococci - angina, lymphadenopathy, bacterial parotitis - epidemiology,                                                  pathogenesis, clinical course, diagnosis, therapy, complicationsTularaemia - history, epidemiology, pathogenesis, clinical course, types of tularaemia, diagnosis, therapy, complicationsDiphtheria - epidemiology, pathogenesis, clinical course, diagnosis, therapy, complications, prophylaxisListeriosis - epidemiology, pathogenesis, clinical course, diagnosis, therapy, listeriosis in                   immunodeficiencyYersiniosis - epidemiology, pathogenesis, clinical course, diagnosis, therapy Parasitic cause of lymphadenopathy:Toxoplasmosis - history, epidemiology, pathogenesis, clinical cause, diagnosis, therapy, toxoplasmosis in pregnancy, toxoplasmosis in immunodeficiency  Lesson V Parasitic diseases Malaria - history, epidemiology, pathogenesis, occurrence of malaria in the world, prophylaxisTypes of malaria, clinical course, diagnosis, therapy, complicationsAmoebosis, giardiosis, echinococcosis, teniarhynchosis, hymenolepiosis, trichinosis (trichinellosis), ankylostomosis, askaridosis, enterobiosis, toxocarosis - etiology, epidemiology, clinical course, diagnosis, therapy, prophylaxis  Lesson VI Infections of the nervous system - bacterial meningitis Epidemiology. Ethiology. Clinical features. Diagnostic approach. Laboratory investigations, CSF features, serological tests, CT, MRI. Differential diagnosis. Treatment. Prognosis. PreventionAcute meningitis - pyogenic: haemophilus meningitis, pneumococcal meningitis, meningococcal infection. Neonatal meningitisPosttraumatic meningitisComplications of meningitis. Brain abscessListeriosis and Listeria meningitisTuberculous meningitisFungal and parasitic infections of CNS (Cryptococcal meningitis, Toxoplasmosis) Septicaemia. Septic shock  Lesson VII Infections of the nervous system - aseptic meningitis Viral meningitis and encephalitis /HSV1, 2, VZ, EBV, CMV, AD, PA, enteroviral, TBEPostinfective and postvaccination encephalitisParotitis epidemica (Mumps) and complications (CNS). Encephalitis herpeticaPoliomyelitis and other enteroviral infections. Polio-like illness. Guillain - Barre syndromePolyneuritisTick borne infections /TBE, Lyme disease (borreliosis), ehrlichiosis, rickettsiosis, tularaemia/LeptospirosisSlow viral infections of the CNS (spongiform encephalopathies)Rabies. Wound septicaemia (P. multocida)BotulismTetanus  Lesson VIIIRespiratory tract infectionsHerpesvirus infections (HSV-1, HSV-2), Chickenpox and herpes zosterInfluenza, parainfluenza, other viral infections of respiratory tract: RS virus, adenovirus, enterovirus, rhinovirus, acute obstructive laryngitis /croup/Mycoplasmal and chlamydial infections /psittacosis, ornithosis/Bacterial respiratory tract infections (Haemophilus influenzae infections, Pertussis and whooping cough syndrome). ActinomycosisAnaerobic infections  Lesson IX AIDS   AIDS as a consequence of HIV infectionHistory, epidemiology, pathogenesis, clinical pictures of various stages of HIV/AIDS, opportunistic infections and tumours associated with AIDS, laboratory and serological diagnosis, differential diagnosis, complications, advances in the treatment of HIV-infection (cART, HAART), vaccines, HIV and society.Fungal infections. New herpetic viruses. Infections in immunocompromised people. Opportunistic infections

Literatura

Mandal, B.K., Wilkins, E.G.L., Dunbar, E.M.,Mayon-White,R.T.: Infections Diseases. Oxford:Blackwell 2004 Hobstová,J. et al.: Infections Diseases. Praha Karolinum 2012 Mandell,G.L., Bennett, J.E., Dolin,R.: Mandell, Douglas and Bennett´s PRINCIPLES and PRACTICE of  INFECTIOUS DISEASES, 7th Edition, New York, Churchill Livingstone 2010 4320 pp. ISBN 978-0-443-06839-3

Garant

MUDr. Věra Štruncovádoc. MUDr. Dalibor Sedláček, CSc.