Předmět Farmakologie (EA0906100)

Na serveru studentino.cz naleznete nejrůznější studijní materiály: zápisky z přednášek nebo cvičení, vzorové testy, seminární práce, domácí úkoly a další z předmětu EA0906100 - Farmakologie, Lékařská fakulta Plzeň, Univerzita Karlova v Praze (UK).

Materiál	Typ	Datum	Počet stažení

Sylabus

PHARMACOLOGY - 3rd year   DENTISTRY SYLLABUS IN DETAILS G E N E R A L      P  H A R M A C O L O G YNames of drugs, Definition of drug (various meaning)Drug originPharmacokinetics, PharmacodynamicsNew drugs -clinical trials, Placebo, Double blind experimentsPharmacokinetic parameters and processesCL, Vd, KE, T1/2, AUC, BioavailabilityWays of administration of drugs, Single and  repeated administrationPermeation of biological membranes by drugsAbsorption of drugsDistribution and redistribution , Blood proteins and drugs, barriersWays of the excretion of drugs, Renal excretionEnterohepatic circulationBiotransformation of drugs, Phases, Reactions, CYP 450;Induction and inhibition of enzymes, Pharmacogenetic, First pass effectEffects of drugs, Specific, non specific effects, Drug target sites, Agonists and antagonists, Type of antagonism. Synergism (additive, potentiation) Dose x effect (graded-quantal)Tolerance, resistence, drug dependence -characteristicsAdverse effects and reactions, Hypersensitivity and idiosyncrasy, Types of allergyAdverse effects of drugs in mouth, Drugs and teethDrugs interaction (with drugs, food and diseases), Contraindications of drugsDrugs in children, drugs in pregnancy, drugs in elderly, drugs and breast feedingCompliance (Adherence) Emergency drugs in dental office S P E C I A L      P  H A R M A C O L O G YPeripheral and central nervous system - Transmitters, Agonists and AntagonistsAutonomic nervous system, Parasympathetic, Sympathetic, Cholinergic transmission, Parasympatomimetics, ParasympatolyticsCholinesterases, Anticholinesterases, Reactivators of cholinesterasesNeuromuscular blocking agents, Drugs against spasm and spasticityAdrenergic transmission, Sympathomimetics, SympatholyticsAnalgesics, Antipyretics, NSAIDs, DMARDs, Orofacial pain, Neuropathic pain,Trigeminal painHistamine, Antihistamines, ImmunomodulatorsGeneral anaesthetics, General anaesthesia, Perioperative drugs, Local anaestheticsAnxiolytics and Hypnoticis in dentistry, AntiemeticsAntiepileptics and Antiparkinsonics and dentistryCNS stimulants, Drug dependence, Antidepressants, Antipsychotic drugsCardiovascular pharmacotherapy and dentistryVitamin K, Anticoagulants, AntiagregantsFibrinolysis, Antifibrinolytics, Control of coagulation, Drugs influencing the haemopoiesisGastrointestinal tract disorders and their pharmacotherapyHormonal therapy (overview) and substitution Glucocorticosteroids, use in stomatologyAnticancer drugs (overview)Antibiotics and Antibacterial drugs in stomatologyAntifungal drugs in stomatologyDrugs acting on oropharynx (local treatment)Dry mouth treatmentNatural AntioxidantsVitamins, Minerals relevant to stomatology (A, B, C, D, E, K and Ca, F, Se)Mercury, Chronic intoxication, AntidotesDrugs in emergency, recommendation for Dentistry office  

Literatura

1. DENTAL DRUG REFERENCE (with clinical implications) 2nd ed.F.A. Pickett, G.T. Térézhalmy (Lippincot Williams and Wilkins)2. MEDICAL PHARMACOLOGY AT A GLANCE 6th ed.Neal M.J. (Chichester, John Wiley and Sons)

Garant

Doc.MUDr. Jaroslav Koutenský, CSc.

Vyučující

MUDr. Monika Bludovská, Ph.D.