Předmět Imunologie (EA0906520)

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Materiál	Typ	Datum	Počet stažení

Sylabus

Immunology - 3rd year - Dentistry 2014/2015  Seminars take place in the seminary room of the Department of Immunology and Allergology - entrance C, 2nd floor, room No 345.  20.02.2015  Mgr. Ochotná Jitka       1. The immune system and its importance for homeostasis. Antigen. Mechanisms of the immune system and their cooperation.2. Component parts of the immune system (organs, cells, substances) and their function.3. Non-specific cellular and humoral immune mechanisms (characteristics, function).4. Specific cellular and humoral immune mechanisms (characteristics, function).5. Phagocytosis (phagocytes, their functions and importance).6. Complement, pathways of activation, biological significance.7. Natural killer cells, their characteristics and function. Interferons.8. Basophiles and mast cells and their role in the immune reactions.6.3.2015  Mgr. Ochotná Jitka9. HLA system  (classes, polymorphism, typing).10. Binding of peptides to MHC. Antigen presentation (function, purpose).11. T-lymphocytes, ontogenesis, selection, surface markers, subpopulations, functions).12. Th1 based immune reaction.13. Th2 based immune reaction.14. Tc based immune reaction.20.3.2015  MUDr. Vachová Martina15. B-lymphocytes - ontogenesis, surface markers, function. Ontogenesis of antibody production.    16. Immunoglobulins (structure, classes). Genetic background of immunoglobulin production. Anti-idiotypes.17. Immunoglobulins (functions of different isotypes)18. Antibodies based immune reaction (primary, secondary).19. Mucous and cutaneous immune system (Barrier functions of the human body and defence mechanisms).20. External regulation of immune response (possibilities, purposes).3.4.2015  Mgr. Ochotná Jitka21. Immune mechanisms of inflammation (local and systemic reaction).22. Physiological mechanisms of regulation of the immune system. Cytokines (classification according to the function).23. Defence against extracellular pathogens (bacteria and unicellular parasites).24. Defence against intracellular pathogens (bacteria, fungi and unicellular parasites.25. Anti-viral defence.26. Defence against multicellular parasites.27. Tumour immunology - tumour antigens, mechanisms of defence.28. Alloimmune reaction. Types of transplantations and immunological examination before transplantation. Immunologically privileged tissues.29. Types of graft rejection and their mechanisms. GvH. Principle of materno-foetal tolerance. Rh incompatibility17.4.2015   Doc. MUDr. Panzner Petr CSc.30. Immunopatological reaction type IV (delayed type). Cutaneous and mucous contact allergy.31. IgE based immunopatological reaction (type I, atopy).32. Allergens. Allergic diseases - causes, symptoms and diagnostics.33. Anaphylaxis (causes, symptoms and treatment).34. Examples of diseases based on immunopathological reaction type I. Treatment.35. Drug allergy.36. IgG and IgM based immunopathological reaction (reaction of hypersensitivity type II).37. Immunocomplex based immunopathological reaction (reaction of hypersensitivity type III).15.5.2015  MUDr. Liška Martin Ph.D.38. Acquired immunodeficiencies - causes, mechanisms involved. AIDS.39. Primary immunodeficiencies - clinical manifestations, examples.40. Hereditary angioedema (pathophysiology, clinical manifestations, treatment).41. Examples of systemic autoimmune diseases. Significance of autoantibodies.42. Examples of organ-specific autoimmune diseases and organoleptic autoimmune diseases. Significance of autoantibodies.

Literatura

Abbas A. K., Lichtman A. H. H., Pillai S.: Basic Immunology: Functions and Disorders of the Immune Systém. Elsevier Health Sciences, 2012Doan T., Melvold R., Viselli S., Valtenbaugh C: Immunology. Lippincott Williams & Wilkins, 2012

Požadavky

Exam questions - Immunology - 3rd year - Dentistry 2014/2015     1. The immune system and its importance for homeostasis. Antigen. Mechanisms of the immune system and their cooperation.2. Component parts of the immune system (organs, cells, substances) and their function.3. Non-specific cellular and humoral immune mechanisms (characteristics, function).4. Specific cellular and humoral immune mechanisms (characteristics, function).5. Phagocytosis (phagocytes, their functions and importance).6. Complement, pathways of activation, biological significance.7. Natural killer cells, their characteristics and function. Interferons. 8. Basophiles and mast cells and their role in the immune reactions.9. HLA system  (classes, polymorphism, typing).10. Binding of peptides to MHC. Antigen presentation (function, purpose).11. T-lymphocytes, ontogenesis, selection, surface markers, subpopulations, functions). 12. Th1 based immune reaction.13. Th2 based immune reaction. 14. Tc based immune reaction.15. B-lymphocytes - ontogenesis, surface markers, function. Ontogenesis of antibody production.16. Immunoglobulins (structure, classes). Genetic background of immunoglobulin production. Anti-idiotypes.17. Immunoglobulins (functions of different isotypes)18. Antibodies based immune reaction (primary, secondary). 19. Mucous and cutaneous immune system (Barrier functions of the human body and defence mechanisms).20. External regulation of immune response (possibilities, purposes).21. Immune mechanisms of inflammation (local and systemic reaction).22. Physiological mechanisms of regulation of the immune system. Cytokines (classification according to the function).23. Defence against extracellular pathogens (bacteria and unicellular parasites).24. Defence against intracellular pathogens (bacteria, fungi and unicellular parasites.25. Anti-viral defence.26. Defence against multicellular parasites. 27. Tumour immunology - tumour antigens, mechanisms of defence.28. Alloimmune reaction. Types of transplantations and immunological examination before transplantation. Immunologically privileged tissues.29. Types of graft rejection and their mechanisms. GvH. Principle of materno-foetal tolerance. Rh incompatibility30. Immunopatological reaction type IV (delayed type). Cutaneous and mucous contact allergy.31. IgE based immunopatological reaction (type I, atopy).32. Allergens. Allergic diseases - causes, symptoms and diagnostics.33. Anaphylaxis (causes, symptoms and treatment).34. Examples of diseases based on immunopathological reaction type I. Treatment.35. Drug allergy.36. IgG and IgM based immunopathological reaction (reaction of hypersensitivity type II).37. Immunocomplex based immunopathological reaction (reaction of hypersensitivity type III).38. Acquired immunodeficiencies - causes, mechanisms involved. AIDS.39. Primary immunodeficiencies - clinical manifestations, examples. 40. Hereditary angioedema (pathophysiology, clinical manifestations, treatment).41. Examples of systemic autoimmune diseases. Significance of autoantibodies.42. Examples of organ-specific autoimmune diseases and organoleptic autoimmune diseases. Significance of autoantibodies.  

Garant

doc. MUDr. Petr Panzner, CSc.